High Performance CO2 Extraction Systems GMP Ready Supercritical 100L/200L/300L/500L

The 100L–500L supercritical CO2 extraction system is a high-performance solution specifically engineered for the European and North American markets, where product quality, safety, and regulatory compliance are critical. This system uses advanced supercritical CO2 technology to extract cannabinoids, terpenes, and essential oils from botanical materials with exceptional precision and consistency. By operating under controlled temperature and pressure, carbon dioxide is converted into a supercritical fluid that offers both high diffusivity and strong solvating power, allowing it to efficiently penetrate plant material and selectively extract target compounds.
Unlike traditional solvent-based extraction methods, this CO2 extraction system eliminates the risk of residual solvents, making it ideal for food-grade, cosmetic, and pharmaceutical-grade applications. The system is designed with a fully closed-loop configuration, ensuring high CO2 recovery rates and minimizing environmental impact. Built with high-grade stainless steel and compliant with GMP-ready standards, it provides a reliable and scalable solution for companies looking to meet strict quality and regulatory requirements in global markets.

Manufacturers targeting the EU and US markets often face strict regulations regarding product purity, safety, and traceability. Traditional extraction methods using ethanol or hydrocarbons can leave residual solvents, require extensive post-processing, and introduce variability in product quality. These issues not only increase operational costs but also create barriers to market entry, especially in regulated industries such , nutraceuticals, and food processing. In addition, manual operation and outdated systems can lead to inconsistent batches, higher labor costs, and increased risk of human error.

This GMP-ready supercritical CO2 extraction system offers a clean, safe, and highly controlled extraction process that meets international standards. The system allows precise adjustment of pressure and temperature to achieve selective extraction, ensuring maximum yield and preservation of sensitive compounds such as terpenes. The integrated multi-stage separation system enables fractionation, allowing different compounds to be collected in a single extraction cycle, improving efficiency and product value.
The fully automated PLC control system provides real-time monitoring and data logging, ensuring repeatable results and easy traceability, which is essential for compliance with GMP and FDA requirements. With a CO2 recovery rate exceeding 95%, the system significantly reduces operating costs while maintaining environmentally sustainable operation. Its modular design allows for easy expansion, enabling businesses to scale production as demand grows.

• Extraction Capacity: 100L / 200L / 300L / 500L
• Working Pressure: Up to 5000 PSI
• Temperature Range: 5°C to 80°C
• CO2 Recovery Rate: ≥95%
• Material: Stainless Steel 316 (GMP-Ready)
• Control System: PLC + Optional SCADA Integration
• Operation Mode: Fully Automatic Closed-Loop
• Separator System: Multi-stage Optional
• Compliance: GMP Design / CE Compatible

This system is widely used in CBD oil extraction, pharmaceutical botanical processing, essential oil production, nutraceutical manufacturing, and high-end cosmetic ingredient extraction. It is particularly suitable for companies exporting to Europe and the United States, where regulatory compliance and product consistency are essential. Businesses producing premium products such as terpene-rich oils, pharmaceutical extracts, or food-grade ingredients benefit from the superior purity and stability offered by CO2 extraction technology.

The extraction process begins by loading dried and prepared botanical material into the extraction vessel. Carbon dioxide is pressurized and heated until it reaches a supercritical state. In this form, CO2 acts as a highly efficient solvent, dissolving target compounds from the plant material. The CO2 carrying these compounds is then transferred into separator vessels, where pressure is gradually reduced. As the pressure decreases, different compounds precipitate and are collected in stages. The CO2 is subsequently cooled, condensed, and recycled back into the system, forming a continuous and efficient closed-loop process.

For companies targeting Western markets, selecting the right CO2 extraction system requires careful consideration of compliance, capacity, and automation. A 100L–200L system is suitable for medium-scale production, while 300L–500L systems are recommended for industrial-scale operations. If your product strategy focuses on high-value extracts such as terpenes or pharmaceutical-grade oils, a multi-stage separation system is essential. Automation level is another key factor, as fully automated systems reduce labor costs, improve consistency, and simplify regulatory compliance. Additionally, ensure that the system is built with SS316 material and designed to meet GMP or CE standards if you plan to export.